Cross-over studies underestimate energy compensation: The example of sucrose-versus sucralose-containing drinks

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Cross-over studies underestimate energy compensation: The example of sucrose-versus sucralose-containing drinks

The vast majority of preload-test-meal studies that have investigated the effects on energy intake of disguised nutrient or other food/drink ingredient manipulations have used a cross-over design. We argue that this design may underestimate the effect of the manipulation due to carry-over effects. To test this we conducted comparable cross-over (n = 69) and parallel-groups (n = 48) studies test...

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ژورنال

عنوان ژورنال: Appetite

سال: 2016

ISSN: 0195-6663

DOI: 10.1016/j.appet.2016.08.113